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In published research, 5-amino-1MQ has been used as a chemical tool to probe NNMT-linked pathways, with preclinical studies examining downstream readouts such as changes in methylation-related metabolites and NAD-associated biochemistry

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The Combination of Quizartinib with Azacitidine or Low Dose Cytarabine Is Highly Active in Patients (Pts) with FLT3-ITD Mutated Myeloid Leukemias: Interim Report of a Phase I/II Trial, oral presentation