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For example, luteolin is effective in therapeutically induced cytotoxicity of cancer cells due to its suppression of cell survival pathways, such as phosphatidylinositol-3′-kinase (PI3K)/Akt, NF-κB, and X-linked inhibitor of apoptosis protein (XIAP), resulting in the stimulation of apoptosis pathways, including the induction of the p53 tumour suppressor [39]

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Implications of ferroptosis in silver nanoparticle-induced cytotoxicity of macrophages