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Besides its important role in the metabolism of sulphur-containing aminoacids, CBS is involved is the production of hydrogen sulphide (H 2 S), an endogenous signalling gasotransmitter involved in the modulation of multiple physiological responses in the vascular, immune and nervous systems
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In the metazoan model Caenorhabditis elegans , the uncharacterized gene H24K24.3 codes for the ortholog of the human ADH5 enzyme
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