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More broadly, chronic alcohol exposure reshapes hepatic macrophage populations by promoting the recruitment of bone marrow-derived monocytes, resulting in a mix of resident Kupffer cells and infiltrating macrophages
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These compounds are generated by the bacterial ALDHs aldA (ALDH50A1), ydcW (ALDH51A1) and yneI (ALDH52A1)/gabD (ALDH5H1), respectively [45]
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