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Pathological changes such as herniated intervertebral disc, inflammatory factor infiltration, and nerve ingrowth are closely related to pain ( 3 The structure and anatomy of IVD 3.1 The anatomy and function of IVD IVDs articulate the vertebral bodies, constituting approximately one-third of the spinal column’s height and providing mechanical support by facilitating load transfer from body weight and muscle activity

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It may help to think of our gut microbiome as a wild garden that provides us with natural medicines and foods