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The approval was based on adequate bridging between the oral granule and approved capsule formulations in a relative bioavailability study in healthy adults (Study 89) and exposure matching between the pediatric patient populations in the SPRINT phase II Stratum I study (capsule formulation, 2 years and older) and the SPRINKLE study (oral granule formulation, 1 year and older)

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Also, BPC 157 counteracted the models resembling positive-like symptoms of schizophrenia[55], and haloperidol-induced catalepsy and gastric ulcers[2]