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Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease

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While both NOX2 and NOX4 are expressed in the macula densa, it is NOX2 that is primarily responsible for NaCl-induced superoxide production, and this is mediated by the translocation to the membrane of the Rac GTPase [186,200]