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M2-like macrophages can be further induced into different subtypes of M2a, M2b, M2c, and M2d under the influence of the respective stimuli ( Figure 1) 22

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This is why bacteriostatic water, rather than plain sterile water, is the standard diluent: its preservative content allows the vial to be safely accessed multiple times without the risk of microbial contamination that plain sterile water carries once a seal is broken