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While damaged neurons switch to the growth mode from their action potential transduction mode, the SCs, macrophages, and endoneurium fibroblasts of the distal nerve stump undergo significant phenotypic changes, thereby creating a growth permissive environment for axon regeneration [35, 36]

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doi: 10.1016/j.bbrc.2009.03.151 278 SchmittC.TurnerD.BoeslM.AbeleM.FroschM.KurzaiO