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To address these challenges, advanced formulations have been developed to enhance nasal residence time and transport efficiency, such as nanoparticles, liposomes, and EVs, which can protect therapeutic agents from degradation and facilitate neuronal delivery (Fan et al., 2018

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This single requirement eliminates the majority of risk, as it was the failure mode in both the Paradigm Peptides adulteration case and what happened to Amino Asylum’s quality concerns