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To simulate the in vitro expansion for ACI, chondrocytes isolated from healthy donors were expanded to population doubling level (PDL) 9, representing chondrocytes ready for implantation
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Psoriasis involves uncontrolled activation of T helper cells (Th1) and (Th17), resulting in the overproduction of pro-inflammatory cytokines, such as IL-1, IL-6, IL-23, IL-22, interferon alpha (IFN-α), and TNF-α (204–206)
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