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Despite the absence of a prolonged anorectic effect, Cagrilintide produced a sustained and significant reduction in body weight in WT mice by −3.4 g after 21 days, while no such effect was observed in KO animals

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10.1016/j.celrep.2021.108690 [DOI] [PMC free article] [PubMed] [Google Scholar] Seelig GF, Colman RF, 1978