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utilized various bioinformatics tools to analyze the expression of Zinc Finger Protein 207 (ZNF 207) in various cancer samples from the TCGA database, such as TIMER 2.0, cProSite, UALCAN, the SangerBox analysis tool, the Gene Expression Profile Interactive Analysis 2 (GEPIA2) tool, the Tumor-Immune System Interaction Database (TISIDB) portal, and the Tumor Immune Dysfunction and Exclusion (TIDE) platform

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The stabilization of HIF-1α under low oxygen levels induces the transcription of glutaminase and GDH, facilitating increased α-KG production under metabolic stress