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Müller et al (190) found that knocking out ACSL4 can protect cells from death induced by the ferroptosis inducer RSL3, indicating that ACSL4 is a reliable biomarker of ferroptosis
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By inhibiting the key enzymes of triglyceride synthesis, i.e., lipin 1 and DGAT, researchers can reshape neuronal lipid metabolism to promote phospholipid synthesis and axonal regeneration (Yang et al., 2020)
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