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Using a long needle risks accidental intramuscular injection, which can lead to dangerously rapid absorption (e.g., causing severe hypoglycemia if insulin is injected into muscle)

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From the study, MSC-Exo successfully transformed the polarization state of LPS-induced RAW264.7 macrophages from the M1 phenotype to the M2 phenotype in vitro , and miR-21-5p is believed to regulate the polarization of macrophages to the M2 phenotype 137