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Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity

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Additionally, AS-IV restored dopaminergic neurons and alleviated PD-associated motor function decline in mice with chemically induced PD, revealing a potential PD therapeutic candidate with senolytic benefits