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Prospective controlled trial of selective parenteral and enteral antimicrobial regimen in fulminant liver failure
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The critical unknowns are: oral bioavailability in humans, tissue distribution (does it reach adipose?), selectivity across the broader methyltransferase family, long-term effects on epigenetic methylation via SAM depletion or elevation, and any interaction with medications that rely on SAM-dependent pathways
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