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The Most Common Vitamin B12 Deficiency Symptoms The following symptoms are particularly common: Disrupted energy metabolism (chronic fatigue and tiredness, difficulty concentrating, muscle weakness) Nerve damage (pain, numbness, tingling, paralysis, coordination problems, memory disorders) Anaemia (poor performance, immunodeficiency) Disruptions to the metabolism of hormones and neurotransmitters (mental/psychological disorders, depressions, psychoses) Digestive disorders (constipation, diarrhoea) Inflammation (mouth, stomach and intestines) A more detailed list of B12 deficiency symptoms is given at the end of this article
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