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consequently, combining SLC7A11 overexpression with glucose starvation would further exacerbate the depletion of TCA cycle intermediates and impairs oxidative phosphorylation in mitochondria, resulting in enhanced cell death
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It went into a real Phase 2/3 Alzheimer’s trial, LIFT-AD, with 554 patients enrolled (NCT04488419), the primary efficacy analysis pre-specified in the 312 of them not taking another Alzheimer’s drug
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