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A significant gap persists regarding the mechanistic role of GADD45β in hepatic lipid metabolism, particularly its interactions with established pathways such as SIRT1/AMPK/sterol regulatory element-binding protein 1 (SREBP1) signaling, which are crucial for maintaining metabolic homeostasis 10,11
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In contrast, cooking cruciferous vegetables before consumption inactivates myrosinase, thus preventing the breakdown of glucosinolates
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