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10.1016/j.diabet.2016.03.008 [DOI] [PubMed] 52.Chapman LE, Darling AL, Brown JE (2015) The association between the biguanide drug metformin and vitamin B 12 deficiency in diabetic patients: a systematic review

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Liposomes are capable of encapsulating both hydrophobic and hydrophilic drugs and also have the potential of fusion with the cell membrane to modulate its fluidity and facilitate the skin penetration and distribution of the loaded drug (Sharma et al., 2018)

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