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Metabolomics of Escherichia coli Treated with the Antimicrobial Carbon Monoxide-Releasing Molecule CORM-3 Reveals Tricarboxylic Acid Cycle as Major Target | Antimicrobial Agents and Chemotherapy
(IIIM-141) has shown promising effects by inhibiting NLRP3 (NOD-like receptor pyrin domain-containing protein 3), a cytoplasmic protein and an inflammasome sensor, protecting against A β - and glutamate-induced neurotoxicities in human neuroblastoma (SH-SY5Y) cells, as well as improving the memory impairment in rats and mice AD models (Bharate et al., 2018)
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The significance of drug-to-lipid ratio to the development of optimized liposomal formulation
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