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5.4 BBR relieves DM through anti-inflammatory mechanisms 5.4.1 BBR modulates gut microbiota as an anti-inflammatory mechanism Studies have demonstrated that changes in gut microbiota can trigger a series of inflammatory responses, while IR and T2DM are closely related to persistent inflammatory states (Singh et al., 2024)

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The lack of standardized dosing protocols, administration techniques, and extended monitoring further hinders clinical translation