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Ways to Prevent Yeast Overgrowth and Avoid Herxheimer Reactions Whether you’ve had an unpleasant Herxheimer reaction and don’t want to go through another or you simply want to prevent yeast overgrowth in the future, there are some simple strategies you can implement to help rebalance your gut flora and keep your digestive tract healthy: Reduce Antibiotic Use: Overuse of antimicrobials is a growing problem