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In theory, a protocol incorporating both peptides simultaneously could engage a broader range of repair mechanisms than either compound alone, covering cell migration, angiogenesis, inflammation modulation, and tissue remodelling in a single intervention

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The TM1 stalk (135-138) of CTR in the Cagri CT-like conformation also undergoes rearrangement relative to the bypass conformation, in which the phenyl of F137 1.28 packs against F15 Cagri , H18 Cagri and S19 Cagri (Fig