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Thiamin deficiency affects both the CNS (central nervous system) and PNS (peripheral nervous system), causing symptoms like confusion, impaired memory and cognition, loss of psychomotor skills, and ataxia (loss of balance)

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Specifically, AHK-Cu might increase the expression of Bcl-2, an anti-apoptotic molecule, while reducing the levels of Bax, a pro-apoptotic counterpart