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GHK-Cu + Epitalon Stack: Evidence, Mechanism Overlap, and Protocol At a glance GHK-Cu sequence / Gly-His-Lys complexed with Cu²⁺ Epitalon sequence / Ala-Glu-Asp-Gly (tetrapeptide) Primary GHK-Cu target / collagen synthesis, Nrf2-driven antioxidant genes, tissue repair Primary Epitalon target / pineal gland regulation, telomerase activation (hTERT), melatonin normalization Mechanism overlap / DNA repair upregulation, oxidative-stress reduction, anti-inflammatory gene modulation Evidence quality for stack / preclinical (animal) + mechanistic