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Phenotypic and functional analysis of macrophages and monocytes from the peritoneum of mice following multiple doses of mRNA NPs showed that the population of immunosuppressive macrophages reduced from an average of 43% in controls to 2.5% in treated mice
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As we age, NAD levels naturally decline, which has been associated with various age-related health issues, including metabolic disorders, neurodegenerative disease, and reduced cellular repair mechanisms
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