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CagriSema leverages synergistic mechanisms: Semaglutide slows gastric emptying, suppresses glucagon, stimulates insulin, and reduces appetite, while Cagrilintide enhances satiety and further delays gastric emptying via brainstem pathways

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“Metabolic burden” explained: stress symptoms and its related responses induced by (over)expression of (heterologous) proteins in Escherichia coli