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For example, micelles of PEO-poly(D,L-lactic acid-co-caprolactone) (PEO-PDLLA) have been used to encapsulate paclitaxel and shown similar in vitro toxicity, fivefold increase in maximum tolerable dose and increased efficacy after intraperitoneal injection in murine P388 leukemia model when compared to the standard formulation with Cremophor EL (71)