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Additionally, EZH2 (Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit), a methyl transferase controlling the epigenetic silencing of specific genes and/or microRNAs by trimethylating Lys27 on histone H3 [9], has been identified as the most deregulated histone modifier in adrenocortical cancer

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The short answer is that it depends on which form of B12 you have