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Preclinical studies indicate that FLASH irradiation not only spares normal tissues but uniquely drives tumor cell death by significantly increasing lipid peroxidation and inducing ferroptosis

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From the defined histological description, a staging model arose in which progression of PD symptoms can be matched with intracellular deposits of pathological α-synuclein aggregates (pαSYN) or Lewy pathology (LP) of the corresponding brain areas (8–11)