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Moreover, 3,4,5-tri- O -caffeoylquinic acid has been shown to enhance pigmentation during the anagen phase of the hair cycle in C3H mice, and human epidermal melanocytes and B16F10 murine melanoma cells by up-regulating the expression of β-catenin
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CR-induced changes in DNA methylation involve both hypomethylated and hypermethylated regions
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