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So TMG plays a key role in a process that can preserve proper cellular function, itself a factor in longevity.42 Other potential benefits of TMG A more limited body of research suggests that TMG may play a role in other areas of health, as well, though the findings aren’t conclusive: Cardiovascular health TMG’s implications for cardiovascular health relate to its action on homocysteine

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However, the passage of 5-methyl-THF through the methionine cycle is limited, especially in situations with high intracellular 5-methyl-THF levels