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However, previous data demonstrated that the tumor growth suppression and metastases by anti-PD-L1 antibody treatment lacked a complete durable response [110, 113], suggesting the existence of resistance mechanisms
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By linking CCR1 signaling with macrophage activation and bladder inflammation, our work provides a mechanistic framework for future studies and support proof-of-concept involvement of the CCL7–CCR1 axis in bladder inflammatory pathology
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