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MTHFR gene mutations are variations in the DNA sequence of the MTHFR gene that can affect the activity of the MTHFR enzyme

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Next, to explore whether the X-IPA system could detect changes to gut permeability induced by intestinal metabolites, gut organ cultures were infused with putrescine, a polyamine compound produced by the gut microbiota which we recently identified as a potent disruptor of the intestinal epithelial barrier 10