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Combination B was found to significantly lower FPG, FPI, HbA 1c , and HOMA index compared to initial values ( p = 0.0001 for FPG
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Drugs like trimetazidine can alleviate myocardial I/R injury by preventing the upregulation of TLR4, MyD88, phospho-NF-κB p65, and the NLRP3 inflammasome [135]
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