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We next further investigated whether the observed bell-shaped profile induced by high concentrations of dimeric macrocycles (3,000 nM) or HGF (30 nM) might be due to off-target inhibition of constitutively activated RTKs, which could potentially transactivate Met phosphorylation
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1949 Jean Schultheis Brechter (Shelter Island, NY), whose grandson is graduating from Cornell next year, tells us that she is “looking forward to the hard copy” of the new publication
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