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These peptides activate MRGPRX2, a mast-cell receptor that fires on positively charged, aromatic molecules and releases histamine into the tissue.⁴ ⁵ Sodium and chloride ions screen the peptide’s positive charge, so the receptor sees less of it and the welt shrinks

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Dynamin 1 (Drp1), also known as Drp1, is a key protein in maintaining the mitochondrial dynamic network (Jin et al., 2021)