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In a mouse model of induced intracerebral hemorrhage, ligustilide and senkyunolide H were shown to exert potent neuroprotective effects against hemorrhagic stroke by inhibiting the Paired Related Homeobox 1 (Prx1)/Toll-like receptor 4 (TLR4)/NF-κB pathway, and subsequent immune and neuroinflammatory damage ( [Cinnamomum camphora(L.)Presl] exhibit significant synergistic effects in promoting neurogenesis and reducing astrocyte generation, with CX playing a central role and Binpian enhancing its effects
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doi: 10.1034/j.1600-0765.2002.01612.x